The landscape setting is Creswell Crags, Nottinghamshire, which Stubbs also used as the background for many of his more dramatic horse and lion subjects. The grey hack here presumably belonged to a nobleman or gentleman. Its stocky build and short legs made it ideally suited for hare coursing, following the greyhound over the rocky moorland.
Between the two animals stands a man dressed in livery, either a groom or hunt servant. The subtle linear rhythms of the horse, groom and greyhound give a sense of movement to the living creatures that is contrasted with the solidity of the looming crags.