This painting is from of a group of fifty illustrations to the Bible commissioned by Blake's patron, Thomas Butts. Its subject is taken from chapter 10 of St Mark's Gospel. Christ, seated beneath a spreading tree, blesses children brought to him while he was preaching. To the left is one of his disciples, who tries to send the children away. Christ tells the disciples:
Suffer the little children to come unto me, and forbid them not: for of such is the kingdom of God... Whosoever shall not receive the kingdom of God as a little child, he shall not enter therein.